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Selpercatinib, 2152628-33-4 (free base), Stock 197g, World biggest supplier.

Selpercatinib, 2152628-33-4 (free base), HPLC 99.45%, HNMR, MASS, HPLC, COA, MSDS we supply.

Selpercatinib, 2152628-33-4 (free base), batch size 1kg, White powder.

Selpercatinib, also known as LOXO-292, is a potent and selective RET inhibitor with antineoplastic properties. LOXO-292 selectively binds to and targets various RET mutants and RET-containing fusion products. This results in an inhibition of cell growth of tumors cells that exhibit increased RET activity. Selpercatinib was approved in M 2020.

Name: SelpercatinibCAS#: 2152628-33-4 (free base)Chemical Formula: C29H31N7O3Exact Mass: 525.2488Molecular Weight: 525.61Elemental Analysis: C, 66.27; H, 5.95; N, 18.65; O, 9.13
Synonym: LOXO-292; LOXO292; LOXO 292; ARRY-192; ARRY192; ARRY 192; Selpercatinib;IUPAC/Chemical Name: 6-(2-hydroxy-2-methylpropoxy)-4-(6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3- yl)pyrazolo[1,5-a]pyridine-3-carbonitrileInChi Key: XIIOFHFUYBLOLW-UHFFFAOYSA-NInChi Code: InChI=1S/C29H31N7O3/c1-29(2,37)18-39-24-9-25(28-21(10-30)13-33-36(28)17-24)20-5-6-26(31-12-20)34-15-22-8-23(16-34)35(22)14-19-4-7-27(38-3)32-11-19/h4-7,9,11-13,17,22-23,37H,8,14-16,18H2,1-3H3SMILES Code: N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OCC(C)(O)C)=CN2N=C1Appearance: Solid powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSOShelf Life: >3 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001

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